Difference between sedating and non sedating antihistamines Man 2man chat line

Skin sensations local itching or burning sensation, flushing and a disagreeable heat.

Stomach pain acid secretion increases; small intestine contracts with crampy pain Respiratory - nose swelling, congestion, sneezing and wheezing.

The drugs of the first antihistamine generation are: promethazine, alimemazine, dexchlorpheniramine, brompheniramine, buclizine, carbinoxamine and doxylamine, are sedating and elicit a drowsiness which can be awkward.

The first-genaration antihistamines have alpha adrenolytic activity which can decrease the vasoconstrictive effect of adrenaline and noradrenaline and an antimuscarinic effect with the corresponding adverse effects.

These receptors both receive histamine as a messenger, but the meaning conveyed is different.

Antihistamines also can be used on an as needed basis for those who experience occasional symptoms or symptoms triggered by exposure to certain irritants such as animal hair, plants, medications, and food products.

Some antihistamines also may be used occasionally to help with sleep.

In addition to this antihistamine effect, they can have parallel pharmacological properties, for example antimuscarinic and adrenolytic effects which must be considered.

It is usual to classify H1-antihistamines into two classes: old ones, called first-generation agents, which are sedating and recent ones, called second-generation agents which have slight or no sedating effects because they do not cross the blood-brain barrier.

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Some antihistamines are found in combination pills that contain other medications.

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